One minor point, the tilt does not change the DOF, rather it tilts the plane of focus. Hence you need to make sure the objects that you want in focus lie in a plane. I suspect it is easier with a wide angle lens.
Some examples can be found on John Shaw's web site. He is a master at using these lenses. (Well, at using any lens!)
One problem I found is that the tilt also introduces a shift, which requires adjustment of the camera position. This is significant for macro work, but I am not sure it matters so much for a wide angle lens. You can make life easier by aligning the tilt and shift axes (the Nikon lens allows this), but then you cannot use the shift for making stitched panoramas with the tilt employed.
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