Christine, more often than not I switch to manual focus and quite often manual exposure + use a tripod whenever possible.
However if you are using a tripod switch to "Aperture Priority", setting a smallish f stop (large f number) to give as much "Depth of Field" as possible.
Alternatively use "Shutter Priority" and set a shutter speed that you know you can handhold, but be aware that DOF is very limited when shooting macro so the slightest movement can throw the subject OOF.
Sometimes a long lens is ideal, attached is a water lilly taken with the Bigma (Sigma 50-500mm), using a macro lens I would have got mighty wet, not to mention the Crocs that where sharing the waterhole with the lillies. The focal length for this shot was 313mm
Harry
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