I've used it with a microscope, (using the older Combine ZM) and have never had any problems with being too close.
I think the secret is not to adjust the focus but to move the camera, (or subject) keeping the magnification constant.
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Mike
Pentax K5ii & Panasonic G5 user (with far too many bits to list)
Member of North Essex Photographic Workshop
Also online with PentaxUser.co.uk, Flickr, MU-43, MFLenses...
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