I use one on my 40 D with a Sigma macro lens which works well but the autofocus with the 70-300 DO is very hit and miss. Canon cameras like your 350 D and my 40D are not specified to autofocus with a lens of f5.6 plus converter so can't really grumble but I find that on central focusing point only often refuses to focus properly but is better on all points active. Not just with the Kenko but any converter. Optical quality of the Kenko is very good.
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