[robski]

A shot I took this evening at 6.30 pm with the last light of the day. ISO 1600.
I am no expert with neat image and I often use the default camera profile. Apart from cleaning up the image a bit I find the main benefit is to get the file size down for the web. I have given the 2 images identical processing in PS except one was noise reduced first. I am sure if you wanted to fiddle in neat image for hours you could get better results.