I use the 501 with my Sigma 500 f4.5 and am very happy with it, it's not quite so big and heavy as the Canon 500 f4, but is still a big lens. I did look at other heads but went for the 501 as it was a familiar style, having used video heads for many years. I also wanted a head that I'd be happy to use with either the camera or my scope - while I'd be happy to use the camera on a ball head I like to have a pan handle when using the scope.
I'm sure the 501 will be fine (I've seen people using this head with the Canon 500 f4) and it's certainly worth giving it a go as you already have it. That said, if I could afford a Wimberly I'm sure I'd change to one.
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